NAD+
NAD+ IV Therapy

Your Journey To Optimized Health and Longevity

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EVERYTHING YOU NEED TO KNOW ABOUT NAD+ IV THERAPY

Nicotinamide adenine dinucleotide (NAD) is a coenzyme molecule that works with the mitochondria that is found in every cell of the body. Mitochondria are membrane-bound cell organelles that generate most of the chemical energy needed to power the cell's biochemical reactions. Naturally found in every cell in the body, NAD helps to maintain DNA integrity and reverse cellular damage. Unfortunately, NAD levels naturally decline as we age.

NAD is an essential life molecule, dubbed an “anti-aging molecule” by leading scientists. This molecule offers many potential therapeutic opportunities by preserving DNA and ensuring healthy cell metabolism. NAD+ works in the mitochondria and increases the length of telomeres, which are the protective caps located at the ends of chromosomes that become shorter as the body ages.

Nicotinamide adenine dinucleotide (NAD+), a potent organic substance or coenzyme, is vital to how the mitochondria (cell powerhouses) performs its duties and plays a crucial role by aiding digestion, cell development, energy metabolism, and other vital processes. So, supplementing with NAD+ can slow this aging process and increase cellular metabolism.

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NAD+ in the Body
Role of NAD+ in the Body

  • ENZYME CATALYST: Due to its ability to bind to and stimulate the activity of other enzymes, NAD+ is classified as a “helper molecule.” Involved in nearly 500 enzymatic events, this potent molecule helps the body stay healthy and functional by supporting the following processes
  • REDUCES GENOMIC INSTABILITY: Genomic instability occurs when our DNA sustains damage and is unable to be repaired. It is proposed as one of the causes of accelerated aging and plays a key role in genetic mutations or cancer development.
    NAD+ plays a vital role in decreasing the occurrence of genomic instability by aiding in damaged DNA repair and also fixing faults made during replication. This crucial role allows efficient transmission of genetic information from one generation to the next via germline cells.
  • INFLAMMATION AND IMMUNITY: Research has shown that NAD+ levels in the body are directly related to the intensity and duration of an immunological response to infection. During an infection, macrophages benefit from elevated levels of NAD+ because it enhances their ability to neutralize the invading pathogen.
  • CRUCIAL IN ENERGY METABOLISM Human cells need energy and if NAD+ levels are low, the body’s ability to make and use energy is hindered. The reactions (Glycolysis, Krebs cycle, oxidative phosphorylation, and fatty acid oxidation) by which the body produces and utilizes energy all depend on NAD+ and low amounts of this cofactor interferes with energy metabolism.
  • GENE EXPRESSION: Genetic expression refers to the process by which the instructions contained in the DNA of cells are translated into the proteins and other substances that the body needs. The successful expression of genes is achieved through NAD+-dependent modification of histone. Since NAD+ is required for this reaction, low amounts of this cofactor may interfere with this process and, in turn, reduce the efficiency with which genes are expressed.
  • CARDIOVASCULAR FUNCTION: Due to its continual contraction and expansion, the heart is the body’s most metabolically active organ. Heart metabolic activity must be kept at a healthy state at all times, and studies have shown that appropriate levels of NAD+ are crucial in maintaining healthy levels and healing after a severe heart disease.
  • IMPROVES RENAL FUNCTION: It is widely known that renal function declines with age and diminishing NAD+ levels may have a part to play. Studies have shown that supplementing with NAD+ can help reduce the risk of acute renal damage by triggering the production of prostaglandin E2. This prostaglandin E2 production aids in repair of kidney damage and improves renal function.
  • CRUCIAL IN LIVER FUNCTION: Maintaining healthy levels of NAD+ in the body is crucial for the liver to do its job properly. Several studies suggest supplementing with NAD+ can improve liver function, protect it against toxic diseases, and speed up recovery after hepatic damage.
  • IMPORTANT IN THE CIRCADIAN RHYTHM: The circadian clock controls the sleep-wake cycle, called the biological clock or the circadian rhythm. The body’s internal clock facilitates adaptation to seasonal or diurnal changes. Studies show that NAD+ levels in cells determine circadian clock precision and performance.
    Also, according to studies, sleepiness during the day, insomnia at night, hormone disruptions, and mental state changes are some potential side effects of a deficit of NAD+. This study highlights how low NAD+ levels disturb the body’s natural circadian cycle
  • IMPROVES NEUROLOGICAL FUNCTION: Maintaining enough NAD+ levels is crucial for the health and survival of brain cells. This was reinforced by studies that showed that after a severe neurological event, NAD+ was important in regenerating the brain’s neurons.
    NAD+ decreases the progression of neurodegenerative disorders by enhancing the body’s natural capacity to repair damaged cells. Also, If NAD+ levels are increased, it leads to the accumulation of proteins that help with cellular communication and improved cognitive function.
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Benefits
Benefits of NAD+ Therapy

  • AUGMENTS ADDICTION THERAPY: Some people may be candidates for intravenous NAD+ therapy for addiction treatment. Patients detoxing from opiates, alcohol, chemicals, nicotine or prescription drugs may benefit from receiving NAD+ by intravenous infusion, which may help lessen the intensity of withdrawal symptoms.
  • RELIEVES CHRONIC FATIGUE: Patients with persistent exhaustion and lack of vitality have been helped by intravenous NAD+ treatment. Increasing ATP levels in the body with exogenous NAD+ supplementation may positively affect energy levels and decrease chronic tiredness.
  • DECREASES RAPID AGING: Restoring and supplementing NAD+ in the body helps improve one’s looks, health, and quality of life by preserving DNA, which might otherwise deteriorate with age due to mechanical stress, faulty replication, or free radical damage.
  • ENHANCES WEIGHT CONTROL When NAD+ levels are restored intravenously, they accelerate the conversion of food into energy, which is subsequently recycled to burn calories, resulting in measurable weight reduction. Also, increasing our resting metabolism through NAD+ is important for keeping fat stores low after a major weight reduction.

    Keeping your NAD+ levels in check helps you avoid metabolic disorders contributing to weight gain and destroying your health.
  • IMPROVES COGNITIVE FUNCTION: How exactly exogenous NAD+ supplementation improves cognitive function is still being researched; however, It has been established that NAD+ has a dual role in the brain, providing both neuroprotection and neurogenesis. IV NAD+ treatment boosts cognitive abilities, including learning, remembering, focusing, and regenerating the brain, as well as general neurological health.
  • ALLEVIATES PAIN: Some people use intravenous NAD+ therapy to alleviate pain, a relatively innovative treatment. Since inflammation is often associated with pain, NAD+, which is known to exert considerable anti-inflammatory activities inside the body, may be utilized to alleviate at least part of the pain experienced by patients.
  • IMPROVES MOOD: When someone is worried or depressed, taking supplemental IV NAD+ therapy can help them create normal quantities of “feel good” neurochemicals in the brain. The brain uses NAD+ to generate mood-regulating neurotransmitters like serotonin, which can improve one’s disposition and reduce the impact of depressive and anxious feelings.
  • ENHANCES ATHLETIC PERFORMANCE: Athletes may benefit from IV NAD+ supplementation in energy, cognition, and response time during games and other sporting activities. In addition, research suggests that NAD+ supplementation can help build muscle and repair damaged muscle, resulting in muscular hypertrophy and muscle hyperplasia.
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IV Therapy
KEY TAKEAWAY

Multiple essential bodily functions depend on NAD+ and would grind to a halt if NAD+ production were to cease. NAD+ promotes healthy senescence, aids in the repair of damaged DNA, increases cellular resistance to stress while shielding brain tissue, and regulates our eating and sleeping habits to meet our physiological demands.

When levels of NAD+ are low, the best approach to guarantee total bioavailability of NAD+ is by intravenous infusion. This implies that your body will be able to take in and use the maximum effective dose of supplementary coenzymes. The anti-aging, immune-boosting, and metabolism- boosting effects of IV NAD+ therapy make it a top choice for replenishing low levels of NAD+.

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Treatment Protocols
Recommended Treatment Protocols

Beginner Protocol Loading dose 2000mg NAD+ over 10 days

Anti-Aging

Day Dose Duration
1 500mg Up to 4 hours
4 500mg Up to 4 hours
7 500mg Up to 4 hours
10 500mg Up to 4 hours

Recommended Monthly Protocol after Loading Dose 2x monthly

Anti-Aging

Day Dose Duration
1 500mg Up to 4 hours
15 500mg Up to 4 hours

3 Day NAD+ Refresher

Refresher Treatment

Day Dose Duration
1 1000mg Up to 8 hours
2 750mg Up to 6 hours
3 500mg Up to 4 hours

Disease Management
Packages for Disease Management

Custom IV Blends

Extended High-Dose Infusions: Our high-dose infusions are designed for treating specific conditions, with protocols that require several days to complete. Each session lasts at least three hours and is tailored for individuals seeking the full benefits of NAD therapy. These treatments are ideal for those wanting maximum results for targeted health concerns.

NAD+ Brain Health: NAD+ IV Therapy for brain optimization and neural restoration, executive functioning & ADD. Program duration – 5 days.

Mood, Metabolism, Brain Fog

Day Dose Duration
1 - 2 1000mg Up to 8 hours
3 750mg Up to 6 hours
4 - 5 500mg Up to 4 hours

NAD+ Addiction
NAD+ Addiction

NAD+ IV therapy for alcohol detox, opioid detox, benzodiazepine detox, stimulant detox. Program duration 10-14 days.

Detox, Disease, Longevity, DNA Repair

Day Dose Duration
1 - 5 1000mg Up to 8 hours
6 - 8 750mg Up to 6 hours
9 - 10 500mg Up to 4 hours

Addiction

Day Dose Duration
1 - 7 1000mg Up to 8 hours
8 - 11 750mg Up to 6 hours
12 - 14 500mg Up to 4 hours

Daily NAD infusions can be highly effective in supporting the treatment of addiction by helping to restore brain function and improve energy levels. NAD works to repair damaged cells, enhance neurotransmitter activity, and reduce cravings, making it easier for individuals to manage withdrawal symptoms. By replenishing essential nutrients, NAD therapy also supports mental clarity, emotional balance, and overall well-being, helping to promote long-term recovery and reduce the likelihood of relapse.

  • NAD+ Depression: NAD+ IV therapy for depression, anxiety & PTSD. Program duration – 4 days. (dosage 250mg-1000mg)
  • NAD+ Lyme Disease: Program duration – 10 days. Please note – Lyme IV Treatments are given every other day. (high dose 1000mg with taper)
  • INAD+ Neurological: NAD+ IV therapy for dementia, Parkinson’s disease & neurological disorders. Program duration – 5 days. (dosage taper 250-750mg)
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NAD+ Treatment
What is Included with NAD+ Treatment

In our IV therapy treatments, we include a variety of essential nutrients to support overall health and well-being. These ingredients work synergistically to enhance immune function, improve energy levels, and promote muscle recovery and enhance the benefits of the NAD+ . We also offer powerful antioxidants like Coenzyme Q10 and glutathione to combat oxidative stress, boost cellular repair, and support anti-aging benefits, ensuring a comprehensive approach to optimizing your health.

  • Additional ingredients in the infusions primes the cells to maximize results of NAD+.
  • Alternating additional ingredients with each infusion is recommended.
  • Even Day: Amino Blend, mineral blend, Q-10 enzyme plus NAD+, and glutathione push
  • Odd Day: B-complex, B-12, Vitamin C, magnesium, calcium plus NAD+ and glutathione push
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NAD+ infusions
Why it is beneficial to include these ingredients into NAD+ infusions

  • Vitamin C is a potent antioxidant with numerous benefits when combined with NAD+:
    Enhanced Antioxidant Defense: Vitamin C helps neutralize free radicals, which can reduce oxidative stress and improve overall cellular health.
    Boosted Immune Function: It supports the immune system, which is crucial for overall health and recovery. Improved NAD+ Efficacy: Vitamin C can help regenerate NAD+, making it more effective in cellular processes.
  • B-Complex Vitamins
    The B-complex vitamins (B1, B2, B3, B5, B6, B7, B9, and B12) play a role in numerous biochemical processes:
    Energy Production: They are involved in converting nutrients into energy, complementing NAD's role in metabolism. Nervous System Health: B-vitamins are essential for nerve function and may help improve mood and cognitive function.
    Cellular Repair and Growth: They support healthy cell function and repair, enhancing the therapeutic benefits of NAD+.
  • Vitamin B12
    Vitamin B12 is particularly important in therapy treatments:
    Red Blood Cell Formation: It supports the production of red blood cells and prevents anemia, which can improve energy levels. Neurological Health: Vitamin B12 supports nerve health and cognitive function, synergizing with NAD+ to support brain health.
  • Magnesium and Calcium:
    Both minerals are essential for various bodily functions and have specific benefits when used with NAD
  • Magnesium:
    Energy Production: Magnesium is crucial for ATP production and overall energy levels.
    Muscle Function: It supports muscle function and relaxation, which can be beneficial for recovery.
    Nervous System Support: It helps in regulating neurotransmitters and maintaining neurological health.
  • Calcium
    Bone Health: Essential for maintaining bone density and strength. Muscle Contraction and Nerve Function: Calcium is vital for muscle contraction and proper nerve signaling, which can enhance the effectiveness of NAD+
  • Amino Acids:
    Amino acids are the building blocks of proteins and play several roles
    Protein Synthesis: They support the repair and building of tissues, complementing NAD’s role in cellular repair. Neurotransmitter Production: Certain amino acids contribute to the production of neurotransmitters, supporting cognitive function and mood.
  • Mineral Blend:
    A mineral blend typically includes essential minerals like zinc, selenium, and potassium, which are important for:
    Enzyme Function: Many minerals act as cofactors for enzymes, enhancing various biochemical reactions in the body. Overall Health Support: They contribute to immune function, antioxidant defense, and fluid balance, supporting the overall effectiveness of NAD+ therapy.
  • Coenzyme Q10 (CoQ10):
    CoQ10 is a compound involved in energy production:
    Cellular Energy Production: It supports mitochondrial function and enhances energy production, working synergistically with NAD+. Antioxidant Properties: CoQ10 also has antioxidant properties, which can help reduce oxidative stress and support overall cellular health
  • Glutathione Push:
    Glutathione is a powerful antioxidant that protects cells from oxidative stress and supports detoxification:
    Enhanced Detoxification: A glutathione push can help to quickly reduce oxidative stress and support the detoxification process. Synergistic Effect: Combining glutathione with NAD+ therapy may enhance the overall antioxidant defense and improve the effectiveness of the treatment.

    Incorporating NAD+ with vitamin C, B-complex vitamins, B12, magnesium, calcium, amino acids, mineral blends, CoQ10, and a glutathione push can offer a comprehensive approach to therapy. Each component supports different aspects of cellular health, energy production, and overall well-being. The synergy among these nutrients can enhance the efficacy of the therapy, leading to better outcomes in terms of energy, cognitive function, cellular repair, and overall health.
    This holistic approach ensures that therapy not only targets specific issues but also supports general wellness and recovery.
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At HI'iaka Health, we take pride in offering cutting-edge regenerative treatments, developed by medical experts through decades of research and innovation, to help you achieve optimal health.

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